- The From address in your app is different to the account you sign in with.
- The account has not been given Send As permission for the shared mailbox, group or alias.
554 5.2.252 / 550 5.7.60: Send As permission denied
Microsoft 365SMTP
The error usually looks like this:
What it means
You signed in as one user but tried to send from a different address, and that user does not have permission to send as it.
Common causes
How to fix it
- Change the From address to match the signed-in account.
- Or ask an administrator to grant Send As permission (Exchange admin center → Recipients → Mailboxes → Delegation).
See also our guide: Account delegation.
Tools to help diagnose it
A free tool provided by Auth-Email
Auth-Email makes your Gmail, Outlook, or other OAuth 2.0 email account available to any IMAP, POP3, or SMTP email client — no app passwords or special configuration needed.